Divisions |
|
| SCHB | Joseph Sabol | Monday, March 26, 2012 |
| Oral Session | |||
| Exponential Technologies: Disruptive Influences and Rapid Advancements in Chemistry - PM Session | |||
| Location: | San Diego Convention Center Monday March 26, 2012 | ||
| Room: | Room 26B | ||
| Cosponsored by: | CEPA, COMSCI | ||
| Organizers: | Lisa Butters | ||
| Presiders: | Lisa Butters | ||
| Duration: | 1:30 pm - 4:20 pm | ||
| Pres Time | Pub # | Presentation Title | |
|---|---|---|---|
| 1:30 pm | Introductory Remarks | ||
| 1:35 pm | 6 |
Digital biology: Life under Moore's Law
Raymond McCauley, The ability to read DNA is in the midst of an unprecedented exponential
change. The Human Genome Project took about $300 million and 11 years
to complete, we now do for under $5000 in a week, and there's no end in
sight. What are the practical applications of this technology? What
are the technical and economic trends driving this revolution? How can
small, agile companies ride along? And where are we going next? | |
| 2:05 pm | 7 |
Broadband magnetic signatures of solvated chemistries
Bennett M. Butters, A low temperature SQUID (super conducting quantum interference device)
based approach to broadband molecular interrogation is discussed with an
emphasis on the technical basis for detection, signal analysis, and the
usefulness of acquired data. Also, presented are the analytical results
of selected materials and the implications to biochemistry. | |
| 2:35 pm | 8 |
Nanostructured materials for large and small molecule selectivity
Robert Meagley, We describe work ongoing at ONE Nanotechnologies, LLC to create and
refine chemoselective films for application as recognition elements in
several sensor platforms. Organic materials and nanocomposites have been
developed that allow gas phase and liquid phase detection of explosives
and chemical agents. Very high surface area interfaces are achieved
through processes suitable for high volume manufacture. Novel strategies
enabling high molecular weight precursors to be used in a plasma
enhanced deposition mode will be shown. Highly structured surfaces shown
to have significant capability to recognize individual proteins from
mixtures will be presented and implications for advanced biomarker
sensing will be discussed. The thrust of this work illustrates the value
of an interdisciplinary approach to advanced material design and
integration in devices. | |
| 3:05 pm | Intermission | ||
| 3:15 pm | 9 |
Sequencing
DNA by looking at it: Seeing chemistry with atoms rather than ensembles
of atoms (or, "Why I left a full professorship to join a startup")
Andrew Bleloch, The development of highly multiplexed sequencing reactions via clonal oligonucleotide clusters has provided the means to reduce the cost of sequencing by roughly five orders of magnitude over the last six years. This "next generation" sequencing has enabled sequencing as a basic tool to inquire the state of DNA variation, the transcriptional levels of the multitude of RNAs, the location of transcriptional cofactors, and many other molecular characteristics that can be expressed as an oligonucleotide. This presentation will summarize the technology and showcase several vignettes of current biological and medical interest. | |
| 3:45 pm | 10 |
Next generation sequencing: Redefining growth beyond Moore's Law
Scott D. Kahn, The development of highly multiplexed sequencing reactions via clonal
oligonucleotide clusters has provided the means to reduce the cost of
sequencing by roughly five orders of magnitude over the last six years.
This "next generation" sequencing has enabled sequencing as a basic tool
to inquire the state of DNA variation, the transcriptional levels of
the multitude of RNAs, the location of transcriptional cofactors, and
many other molecular characteristics that can be expressed as an
oligonucleotide. This presentation will summarize the technology and
showcase several vignettes of current biological and medical interest. | |
| 4:15 pm | Concluding Remarks | ||
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